High Purity Peptide CAS 910463-68-2 Ozempic Powder

910463-68-2 Semaglutide

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Detailed Product Information
Product Name : Semaglutide
Trade Name: Ozempic/Rybelsus
CAS No.:910463-68-2
Molecular Formula: C20H35NO2
Molecular Weight:321.5g/mol
Purity : 98% HPLC
Appearance:  Lyophilized Powder
Typical use: Type 2 Diabetes Medicine
Shelf Life :2 years
Storage:Refrigeration keep dry and away from light.


Semaglutide(910463-68-2) is an anti-diabetic medication that is sold under brand names such as Ozempic, Wegovy, and Rybelsus. It is used to treat type 2 diabetes and manage chronic weight. The drug functions similar to human glucagon-like peptide-1 (GLP-1) by increasing insulin secretion, which leads to improved sugar metabolism. It is distributed as a metered subcutaneous injection in a prefilled pen, or as an oral form. One of its advantages over other antidiabetic drugs is that it has a long duration of action, thus, only once-a-week injection is sufficient.


Product Name: Semaglutide
Synonyms: Sermaglutide;Semaglutide impurity;Sermaglutide USP/EP/BP;semaglutide;Sermaglutide CAS 910463 68 2;Ozempic, Rybelsus;Ozempic;Semaglutide (H-7894.0001)
CAS: 910463-68-2
MF: C187H291N45O59
MW: 4113.57754
EINECS: 203-405-2
Product Categories: GLP;PP;APIs;API;910463-68-2
Mol File: 910463-68-2.mol

Rybelsus (semaglutide) is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.
Rybelsus is usually given after other diabetes medicines have been tried without success.

The FDA approved once-weekly semaglutide injection for chronic weight management in adults with obesity or with overweight and at least one weight-related condition, according to an agency press release.

Weekly semaglutide 2.4 mg (Wegovy, Novo Nordisk), a GLP-1 receptor agonist, is the first-approved drug for chronic weight management in adults with general obesity or overweight since 2014. Semaglutide is indicated for chronic weight management in adults with a BMI of 27 kg/m² or greater who have at least one weight-related comorbidity, such as type 2 diabetes or hypertension, or in adults with a BMI of at least 30 kg/m²

Semaglutide 1 mg injection (Ozempic) was first approved as a treatment for type 2 diabetes in 2017.

Safety and efficacy of semaglutide 2.4 mg was assessed in four 68-week trials. Three were randomized, double-blind, placebo-controlled trials, including 16 weeks of dose increases, and one was a double-blind, placebo-controlled, randomized withdrawal trial in which patients assigned semaglutide either continued treatment or switched to a placebo

Semaglutide 2.4 mg should not be used in combination with other semaglutide-containing products, other GLP-1 receptor agonists or other products intended for weight loss, including prescription drugs, over-the-counter drugs and herbal products, according to the release. Semaglutide 2.4 mg has not been studied in patients with a history of pancreatitis.

This is a once-weekly injectable, which is more tolerable way of managing obesity vs. other treatments. The STEP study data showed semaglutide 2.4 mg crosses the magic threshold of 10% weight loss for many people who received it. This is another tool that will allow clinicians to better manage obesity.


  • Diabetes Type 2 Medicine
  • Oral GLP-1RA Medication
  • Weight Loss
  • Diabetes Mellitus
  • Obesity
  • Diabetic Coma (in DM Type II)
  • Diabetic Ketoacidosis (in DM Type II)
  • Cardiovascular Risk Reduction

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Appearance White powder.
Purity 99%min
Single Impurity (HPLC)  1.0%max
Amino Acid Composition  ±10% of theoretical
Peptide Content (N%)  ≥80.0%
Water Content(Karl Fischer)  ≤6.0%
Acetate Content (HPIC) ≤15.0%
MS(ESI) Consistent
Mass Balance  95.0~105.0%
Specific Rotation (20/D)  -65.0~-75.0°(c=0.5 1%HAc)
Solubility H 2 O:40 mg / mL
Storage condition -20ºC
Shelf life 2 years









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