China GMP Quality Factory Direct Supply 99% Purity Roflumilast Chemical Raw Material Powder CAS: 162401-32-3

162401-32-3 Roflumilast, wickr : wjadmin whatsapp +86 15512120776

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Biological Agents   Chemical Enterprise

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Product Description
China GMP Quality Factory Direct Supply 99% Purity Roflumilast Chemical Raw Material Powder CAS: 162401-32-3


 

Product Description

Product Name Roflumilast
Alias B 9302-107, BY 217, BYK 20869, Daxas
CAS 162401-32-3
MF C17H14Cl2F2N2O3
MW 403.21
EINECS 223-583-8
Purity 99.50%
Grade Pharmaceutical Grade
Appearance white Crystalline Powder

 

Product Introduction

Roflumilast (trade names Daxas, Daliresp) is a drug that acts as a selective, long-acting inhibitor of the enzyme phosphodies phosphodiesterase-4 (PDE-4). It has anti-inflammatory effects and is used as an orally administered drug for the treatment of inflammatory conditions of the lungs such as chronic obstructive pulmonary disease (COPD).

Roflumilast is an oral selective phosphodiesterase 4 (PDE4) inhibitor. It is a benzamide compound and is currently the only phosphatase IV (PDE-4) inhibitor approved for oral treatment of respiratory diseases. Through Chemicalbook, it selectively inhibits PDE4 and blocks the transmission of inflammatory response signals, thereby inhibiting lung tissue damage caused by respiratory diseases such as COPD and asthma. It has been shown to inhibit COPD-related inflammation with a new mode of action.

Product Usage

Selective phosphodiesterase 4(PDE4) inhibitor. Antiasthmatic; in treatment of chronic obstructive pulmonary disease

COA

Items Standards Results
Appearance White or off-white solid powder Complies
Identification By IR Complies
By HPLC Complies
Solubility Highly soluble in methano,soluble in
ethanol,acetonitril; slightly soluble in water
Complies
Melting Point 156ºC~160ºC 157.6ºC~158.5ºC
Water Content ≤ 0.50% 0.25%
Residue on Ignition ≤ 0.10% 0.05%
Heavy Metal ≤10ppm Complies
Residual Solvents Dichloromethan: ≤100ppm ND
Hexan: ≤200ppm ND
Ethyl acetat: ≤500ppm ND
Tetrahydrofura: ≤100ppm ND
Related Substances Impurity A: ≤0.10% 0.07%
Impurity B: ≤0.10% 0.08%
Any other single impurity: ≤0.10% 0.08%
Total Impurities: ≤0.50% 0.15%
Assay
(HPLC basis on drying)
98.0%~102.0% 99.99%
Reference Standard In-house Standard
Conclusion The product complied to In-house standard.

 

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China GMP Quality Factory Direct Supply 99% Purity Roflumilast Chemical Raw Material Powder CAS: 162401-32-3

 

 

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Packing & Delivery
Company Profile
Our company is located in the center of politics, military, economy, culture and science and education in South China.We are a professional manufacturer engaged in the research, development, production, sales and service of surfactants, biological agents, organic chemistry, oilfield chemicals and disinfectant raw materials.We can offer a wide range of products to meet the changing needs of the market.Custom orders are welcome.We are committed to strict quality control and thoughtful customer service, and our experienced staff are always available to discuss your requirements and ensure complete customer satisfaction.With an annual production capacity of 10,000 tons/year, we can easily meet your large orders.If you are interested in any of our products or would like to place a custom order, please contact us.We will do our best to meet your needs.
Our Advantages
Exhibition
FAQ
Q1. Can I have a sample order for your products?
A: Yes, we welcome sample order to test and check quality. Mixed samples are acceptable. We provide free samples, but the freight will be borne by you, and the cost will be returned to you or deducted from your order later.
Q2. What about the lead time?
A:Sample needs 1-3 days, mass production time needs 1-2 weeks.
Q3. Do you have any MOQ limit for order?
A: Low MOQ, 10-100g for sample checking is available
Q4. How do you ship the goods and how long does it take to arrive?
A: We usually ship by DHL, UPS, FedEx or TNT. It usually takes 3-5 days to arrive. Airline and sea shipping also optional.
Q5. How about the packing?
A: Usually we provide the packing as 25 kg / bag or carton. Of course, if you have special requirements on them, we will according to you.
Q6: how do you control quality?
A: We will make samples before mass production and start mass production after sample approval. 100% inspection during production and random inspection before packaging.
Q7: how to contact us?
A: Pls send us the product information you are interested in. You will get a reply within 24hours.
Q8: which payment method do you accept?
A: For small orders, you can pay by wire transfer, Western Union, Moneygram transfer, Bank Tansfer, Bitcoin or Alibaba.
Q9: can you give me a discount?
A: Of course, it depends on your quantity
Q10: how to confirm product quality before placing an order?
A: you can get free samples for some products. You only need to pay for transportation or arrange express delivery to take samples for us. You can send us your product specifications and requirements. We will make products according to your requirements.
Q11: how do you deal with quality complaints?
A: first of all, our quality control will reduce the quality problem to nearly zero. If the actual quality problem is caused by
us, we will send you free goods for replacement or refund.
Q12: Are you trading company or manufacturer?
A: We are chemical factory in China. So we can provide wholesale price.

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