Wanjiang supply Berberine 99.99% Yellow Crystalline Powder CAS 2086-83-1

Berberine CAS 2086-83-1

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Biological Agents   Chemical Enterprise



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Coptis chinensis was widely used in China as a folk medicine by Shennong around 3000 BC. Coptis chinensis was firstly described in the ancient Chinese medical book The Divine Farmer’s Herb-Root Classic. Coptis chinensis was used to treat intestinal bacterial infections and antipyretic analgesic for thousands of years ago
Coptis chinensis also called zhilian, chuanlian, weilian, jizhualian, shanglian, and xuanlian in Chinese history. Coptis chinensis was accepted by most physicians, and the Chinese pharmacopoeia also uses Coptis chinensis as its official name . Coptis chinensis mainly grows in Anhui, Hunan, Sichuan, and Yunnan and has been cultivated in Sichuan since the Ming dynasty, which has a long history of cultivation. Other species of Coptis chinensis from different places were used as medicine. However, commodity circulation of wild Rhizoma coptidis has not been formed . Coptis chinensis is national three level protection plants at present and majorly produced in Shizhu of Chongqing, West Hubei, Shanxi, and Gansu.
Berberine is a quaternary ammonium salt from the protoberberine group of isoquinoline alkaloids. It is found in some plants such as huanglian 黄连 (Rhizoma coptidis), huangbo黄柏 (Phellodendri Chinensis Cortex), sankezhen三颗针 (Berberidis Radix), and so on.
The components of Coptis chinensis which have antibacterial and antiinflammatory effects are original alkaloid berberine class, including berberine, coptisine, palmatine, epiberberine, columbamine, jatrorrhizine, worenine, and magnoflorine, with berberine having the highest content (5–8%).


Berberine Basic information
Product Name: Berberine
CAS: 2086-83-1
MF: C20H18NO4
MW: 336.37
EINECS: 218-229-1
Product Categories: chemical reagent;pharmaceutical intermediate;sy;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract
Mol File: 2086-83-1.mol
Berberine Structure
Berberine Chemical Properties
Melting point  204-206 °C (dec.)
Boiling point  486.8°C (rough estimate)
density  1.2976 (rough estimate)
refractive index  1.5800 (estimate)
storage temp.  Inert atmosphere,Room Temperature
pka 2.47(at 25℃)
color  White to yellow crystals


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  1. Inner double plastic bags----25kg/Fiber drum (35*35*45cm, GW: 28kg, NW: 25kg);
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Q12: Are you trading company or manufacturer?
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