Top quality Tetracaine hcl 136-47-0

CAS 136-47-0 Tetracaine hcl

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Tetraca Hcl Detailed Description:

Product name Tetraca hydrochloride
CAS No. 136-47-*
Molecular formula C15H25ClN2O2
Molecular weight 300.82
EINECS number 205-248-5
Purity >99%
Standard Pharmaceutical Grade
Appearance White or almost white crystal powder

 

What is Tetraca Hydrochloride?

1. The origin of tetraca hydrochloride
Tetraca HCl is synthesized from 4-butylaminobenzoic acid. The ethyl ester is formed through an acid-catalyzed esterification reaction. Base-catalyzed transesterification is achieved by boiling the ethyl ester of 4-butylaminobenzoic acid with excess 2-dimethylaminoethanol in the presence of a small amount of sodium ethoxid.

2. Uses of Tetraca Hydrochloride
Tetraca (INN, also known as amethocaine; trade name Pontocaine. Ametop and Dicaine) is a potent local anesthetic of the ester group. It is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia.
In biomedical research, tetraca is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. Tetraca is an allosteric blocker of channel function. At low concentrations, tetraca causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetraca blocks release completely.
 
3. What is the difference between the anesthetic intensity of tetraca hydrochloride powder and lidocain, procain ?
 Local anesthetics: Tetraca base >tetraca hcl>lidocain>lidcain hcl> benzocain> procain>procain hcl, but the corresponding side effects will also increase.

 

 

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Hot Selling Products                                                                          

Products name CAS No. Products name CAS No.
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Pramoxine HCI 637-58-1 Proparacaine HCI 5875-06-9
Articaine HCI 23964-57-0 Mepivacaine HCl 1722-62-9
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Oxiracetam 62613-82-5 Diltiazem 42399-41-7
Tryptamine 61-54-1    
Topiramate 97240-79-4 Phenibu 1078-21-*
Europiumchloride 10025-76-0 BM* 203

 

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